Mono-Methyl Arginine [mme-R] MultiMab Rabbit mAb mix 8015S from Cell Signaling Technology

Product Specs
ItemMono-Methyl Arginine [mme-R] MultiMab Rabbit mAb mix
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number8015S
Quantity100 µl
ApplicationsW, IP, E-P
ReactivityAll
HostRabbit
ClonalityMonoclonal
Research AreaMotif Antibodies
TargetArginine monomethyl (R-Me) methylate
ModificationsArginine monomethyl (R-Me) methylate
IsotypeIgG

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA miceEMBO Molecular MedicineNovember 8, 2023Anna J Kordala, Jessica Stoodley, Nina Ahlskog, Muhammad Hanifi, Antonio Garcia Guerra, Amarjit Bhomra, Wooi Fang Lim, Lyndsay M Murray, Kevin Talbot, Suzan M Hammond, et al.(Cell Signalling, 9715), Vinculin (Sigma, 062M4762), HNRNPA1 (Santa Cruz, 4B10), MMA (Cell Signalling, 8015), ADMA (Sigma Aldrich, 07‐414), SDMA (Cell Signalling, 13222), β‐tubulin (Abcam, 108342), and FAST green

(2) Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progressionJournal of Translational MedicineSeptember 15, 2023Wensheng Deng, Jiaoyu Ai, Wanlin Zhang, Zhenyu Zhou, Muqi Li, Likun Yan, Lidong Zhang, Zongjing Huang, Ziyi Wu, Junhua Ai, et al.Santa Cruz Biotechnology), 4-HNE (1: 1000, ab46545, Abcam), HSPA8 (1: 4000, 10654-1-AP, Proteintech), MMA (1:1000, 8015S, CST), sDMA (1:1000, 13222S, CST), GAPDH (1:2000, 60004-1-Lg, Proteintech). Next, the PVDF membranes

(3) Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesisInternational Journal of Biological SciencesJuly 15, 2023Eunji Kim, Laily Rahmawati, Nur Aziz, Han Gyung Kim, Ji Hye Kim, Kyung-Hee Kim, Byong Chul Yoo, Narayana Parameswaran, Jong-Sun Kang, Hoon Hur, et al.following primary antibodies were used: anti-LC3B, anti-MME-R, anti-ADME-R, anti-Myc, and anti-Flag (3868, 8015, 13522, 2276, and 8146; Cell Signaling Technology, Beijing, China). Antibodies recognizing β-actin,

(4) PRMT1 reverts the immune escape of necroptotic colon cancer through RIP3 methylationCell Death & DiseaseApril 1, 2023Lian Zhang, Yujiao He, Yi Jiang, Qi Wu, Yanchen Liu, Qingqiang Xie, Yuxiu Zou, Jiaqian Wu, Chundong Zhang, Zhongjun Zhou, et al.37705), HA (16B12) (Biolegend, 901515), FLAG M2 (Sigma, F1804), Mono-Methyl Arginine [mme-R] (CST, 8015), Asymmetric Di-Methyl Arginine Motif [adme-R] (CST, 13522), Symmetric Di-Methyl Arginine Motif [sdme-RG]

(5) PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinomaNature communicationsFebruary 23, 2023Wang K, Luo L, Fu S, Wang M, Wang Z, Dong L, Wu X, Dai L, Peng Y, Shen G, et al.(MA1-21315, 1:2000) were purchased from ThermoFisher Scientific. Antibodies against mono-methyl arginine (8015, 1:1000), asymmetric di-methyl arginine (13522, 1:1000), and symmetric di-methyl arginine (13222, 1:1000)

(6) Arginine Methylation of Integrin Alpha-4 Prevents Fibrosis Development in Alcohol-Associated Liver DiseaseCellular and molecular gastroenterology and hepatologyJanuary 1, 2023Schonfeld M, Villar MT, Artigues A, Weinman SA, Tikhanovich I.Cell Signaling #77397 F4/80 Cell Signaling #70076 Integrin α4 Cell Signaling #4749 Methyl-R Cell Signaling #8015 Deoxyuride-5´-Triphosphate Nick End Labeling Assay Deoxyuride-5´-triphosphate nick end labeling assay

(7) PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTENJournal of CancerJanuary 1, 2023Wang X, Xu W, Zhu C, Cheng Y, Qi J.lysis buffer. Immune precipitates were assayed by western blotting with an anti-MMA antibody (1:1000, #8015S, CST). Statistical analysis The experimental data were statistically analyzed using SPSS software

(8) The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biologyMolecular MetabolismOctober 1, 2022Tiffany L. vanLieshout, Derek W. Stouth, Nicolas G. Hartel, Goutham Vasam, Sean Y. Ng, Erin K. Webb, Irena A. Rebalka, Andrew I. Mikhail, Nicholas A. Graham, Keir J. Menzies, et al.antibodies were used: CARM1 (1:5000; A300-421A; Bethyl Laboratories, Montgomery, Texas, USA), MMA (8015, Cell Signaling, Danvers, MA, USA), SmBme0 (1:1,000; SAB2102256; Millipore Sigma, Etobicoke, ON, Canada),

(9) Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkersAmino AcidsApril 1, 2022Alistair James Marsden, David R. J. Riley, Stefan Birkett, Quentin Rodriguez-Barucg, Barbara-ann Guinn, Sean Carroll, Lee Ingle, Thozhukat Sathyapalan, Pedro Beltran-Alvarezproteins transferred to PVDF membranes (GE Healthcare). We used two validated α-ArgMe antibodies (#8015 and #8711, Cell Signalling Technologies) and an α-keratin-83 antibody (ab174272, Abcam) at 1:1000 dilutions

(10) The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPDNature communicationsMarch 14, 2022Günes Günsel G, Conlon TM, Jeridi A, Kim R, Ertüz Z, Lang NJ, Ansari M, Novikova M, Jiang D, Strunz M, et al.(Thermo Fisher Scientific) were crosslinked with 4 μg anti-mono-methylated arginine antibody (Cat. No. 8015, Cell Signaling Technology) per IP. About 50 ug of protein from wild-type and Prmt7null clone MH-S cells

(11) Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferasesiScienceSeptember 24, 2021Maxim I. Maron et al.for western blot analysis. Antibodies used in the western blot include: FUS and TAF15 (see above), Rme1 (CST 8015S), Rme2s (CST 13222S), Rme2a (CST 13522S); Secondary antibody was TidyBlot-HRP (Bio-Rad STAR209P). Histone

(12) Arginine methylation of METTL14 promotes RNA N⁶-methyladenosine modification and endoderm differentiation of mouse embryonic stem cellsNature communicationsJune 18, 2021Liu X, Wang H, Zhao X, Luo Q, Wang Q, Tan K, Wang Z, Jiang J, Cui J, Du E, et al.anti-mono and dimethyl arginine (1:1000, Abcam, ab412), rabbit anti-mono-methyl arginine (1:1000, CST, 8015 S), rabbit anti-GAPDH (1:10000, Proteintech, 60004-1-Ig), mouse anti-flag (1:3000, MBL, M185-3L), mouse

(13) Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesisCell metabolismMay 4, 2021Wang YP, Sharda A, Xu SN, van Gastel N, Man CH, Choi U, Leong WZ, Li X, Scadden DT.AB_2237696 Rabbit monoclonal anti-Mono-Methyl Arginine (clone Me-R4-100),Cell Signaling Technology,Cat#:8015; RRID: AB_10891776 Mouse monoclonal anti-CARM1,Arigo Biolaboratories,Cat#: ARG53996 ,, Bacterial

(14) Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growthNature communicationsMarch 29, 2021Li WJ, He YH, Yang JJ, Hu GS, Lin YA, Ran T, Peng BL, Xie BL, Huang MF, Gao X, et al.listed as following: Rabbit monoclonal anti-mono-methyl arginine [mme-R] (Cell Signaling Technology, 8015S, 1:2000); PTMScan® mono-methyl arginine Motif [mme-RG] Kit (Cell Signaling Technology, 12235, for immunoenrichment);

(15) Protein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine modelPLOS Neglected Tropical DiseasesMarch 2, 2021Juliana Alcoforado Diniz et al.10600003), which were incubated with antimonomethyl arginine antibody (Cell Signaling Technologies—REF 8015S), following manufacturer’s instructions. The antigen-antibody interaction was detected using an ECL

(16) PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancerOncogeneFebruary 1, 2021Yin XK, Wang YL, Wang F, Feng WX, Bai SM, Zhao WW, Feng LL, Wei MB, Qin CL, Wang F, et al.(cat. no. D160716; Sangon Biotech, Shanghai, China), pan-ADMA (cat. no. 13522; CST), pan-MMA (cat. no. 8015; CST). Images were captured with ChemiDocTM Imaging System (Bio-Rad, Hercules, CA, USA), and the band

(17) Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissuesScientific reportsDecember 17, 2020Noto PB, Sikorski TW, Zappacosta F, Wagner CD, Montes de Oca R, Szapacs ME, Annan RS, Liu Y, McHugh CF, Mohammad HP, et al.primary antibodies were used: anti-monomethylated arginine (mme-R, Cell Signaling Technology (CST), #8015, 1:1,000 dilution), anti-symmetric dimethylated arginine (sdme-RG, CST, #13222S, 1:1,000 dilution),

(18) Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress responseNature communicationsMay 14, 2020Szewczyk MM, Ishikawa Y, Organ S, Sakai N, Li F, Halabelian L, Ackloo S, Couzens AL, Eram M, Dilworth D, et al.lines were purchased from Cedarlane and Sf9 cells (#11496015) from ThermoFisher Scientific. Anti-Rme1 (#8015, 1:1000), anti-Rme2s (#13222, 1:2000), anti-mouse IgG Alexa Fluor 488 (#4408, 1:1000), anti-TIAR (#8509,

(19) The arginine methyltransferase PRMT5 and PRMT1 distinctly regulate the degradation of anti-apoptotic protein CFLARL in human lung cancer cellsJournal of Experimental & Clinical Cancer ResearchDecember 1, 2019Mingyue Li, Wentao An, Linyan Xu, Yidan Lin, Ling Su, Xiangguo Liu(America). The CFLARL (ALX-804-961-0100) antibody was purchased from Enzo Biochem. The monomethyl arginine (8015S), CASP8 (9746 L) and PARP-1 (#9542) antibodies were purchased from Cell Signaling Technology (Boston,

(20) Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine MethylationCancer cellAugust 12, 2019Fong JY, Pignata L, Goy PA, Kawabata KC, Lee SC, Koh CM, Musiani D, Massignani E, Kotini AG, Penson A, et al.,Cell signaling,#13522; RRID: AB_2665370 Anti-PRMT1,Cell signaling,CST #2449; RRID: AB_2237696 Anti-MMA,Cell signaling,#8015; RRID: AB_10891776 Anti-EZH2,Cell signaling,CST #5246; RRID: AB_10694683 Anti- γH2Ax,Cell signalling,CST

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Mono-Methyl Arginine [mme-R] MultiMab ™ Rabbit mAb mix

Mono-Methyl Arginine [mme-R] MultiMab Rabbit mAb mix from Cell Signaling Technology

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Cell Signaling Technology

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Mono-Methyl Arginine [mme-R] MultiMab Rabbit mAb mix from Cell Signaling Technology

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